CASE STUDY: ORAL HYPOGLYCEMIC DRUGS OVERDOSE INDUCED GENERALISED TONICCLONIC SEIZURES

Metformin is an oral hypoglycemic agent of the biguanide class, and glimepiride sulfonylurea class frequently used to treat Type-II diabetes mellitus. Under certain conditions, overdose or long-term use metformin can cause lactic acidosis hypoglycemia. severe hypoglycemia in absence other anti-diabetic drugs. Potential mechanisms metformin-induced include decreased hepatic glucose production, absorption, low intake. Hypoglycemia, turn, leads loss consciousness, headache, confusion, neurological symptoms such as insomnia, delirium, rare conditions may lead coma, seizures, death. Here, this case study 23-years-old female patient non-diabetic presented with alleged consumption (8 g), (32 mg) three-episodes generalized tonic-clonic seizures (GTCS), fever chills, consciousness. In general, diabetic patient’s condition be more often due drug overdosage dietary restrictions. However, patients, considered a jeopardy situation because it several fatal effects.